I think that many babblers are aware of the many demands to rename the street named for Lord Jeffrey Amherst, because of his history of using smallpox-infested blankets as a means of bacteriological warfare and genocide against Amerindian peoples who had taken the side of New France. It is no surprise that such tactics were more readily used against foes seen as "savages".
But some have expressed a desire to rename it for a Québécois figure such as Jacques Parizeau (remember, not only a politician, but an important figure in the Quiet Revolution) and while I certainly think Parizeau deserves a street somewhere, writing this historical wrong calls for a street name that is either Indigenous or commemorative of an Indigenous event, feast or concept.
If it is a name in French, it could be something like Rue de la Grande paix, or rue des Deux-Esprits (a positive Indigenous concept relating to LGBT+ people, as it is an important street in what is now the Gay Village), but personally I'd prefer an Indigenous name. In any case, to right the historical wrong, it must relate to Indigenous peoples' history, culture or world views, not Québécois ones.
And renaming must not mean forgeting. Boulevard Alexis-Carrell has become boulevard Rita Levi-Montalcini (another Nobel prize winner and an extraordinary woman who I like seeing honoured).